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Property CitySanta Ana

1 to 6 out of 18 properties

Santa Ana Panama Real Estate โ€“ Historic Homes, Apartments & Investment Opportunities

Located next to Casco Viejo, Santa Ana is one of Panama Cityโ€™s most historic neighborhoods, now undergoing an exciting period of revitalization. Known for its colonial architecture, traditional plazas, and authentic local culture, Santa Ana Panama real estate for sale and rent offers affordable apartments, renovated homes, and investment properties in the heart of the city.

With its central location, Santa Ana appeals to buyers and renters looking for city living at a more accessible price point, while still being just minutes from Panamaโ€™s top dining, nightlife, and cultural attractions in Casco Viejo.

Why Choose Santa Ana Panama?

Historic Character โ€“ Colonial buildings, traditional plazas, and vibrant street life.

Central Location โ€“ Walking distance to Casco Viejo and easy access to downtown.

Investment Potential โ€“ Increasing demand as revitalization projects continue.

Affordable Real Estate โ€“ More accessible pricing compared to Casco Viejo.

Types of Properties in Santa Ana

Restored Colonial Homes for Sale โ€“ Charming residences with historic details.

Apartments & Condos for Sale โ€“ Renovated units in boutique buildings.

Homes & Apartments for Rent โ€“ Long-term and short-term rental options.

Investment Properties โ€“ High rental demand among young professionals and expats.

Land for Development โ€“ Opportunities for new projects in a growing district.

Living in Santa Ana Panama

Life in Santa Ana blends old-world charm with modern convenience. Residents enjoy access to local markets, historic plazas, and a growing cafรฉ and restaurant scene, all within walking distance of Casco Viejo. As revitalization projects continue, Santa Ana is quickly becoming one of the most dynamic and expat-friendly neighborhoods in Panama City, making it a smart choice for both lifestyle and investment.

Interested in Santa Ana Panama real estate?
Browse our listings of homes, apartments, and investment properties for sale and rent in Santa Ana and let Panama Equityโ€™s experts guide you through this fast-growing neighborhood.

View Property

Airbnb STR Friendly New Condo Development in Historic District

Not every condo offers the…

Bedrooms
2
Bathrooms
2
Area
84 m2
For Sale

$345,000

By Zelda PJ-0752-09

View Property

Lock Off Two Bedroom Condo for Sale at Vanguardia

One of the biggest decisions…

Bedrooms
2
Bathrooms
2
Area
96.5 sq ft
For Sale

$475,000

By Zelda PJ-0752-09

View Property

Modern One Bedroom Condo for Sale at Vanguardia

Looking for a one-bedroom condo…

Bedrooms
1
Bathrooms
2
Area
61 m2
For Sale

$305,000

By Zelda PJ-0752-09

View Property

Path of Progress Development Opportunity in Santa Ana

This corner development parcel sits…

Lot Size
0.112 acres 453 m2
For Sale

$699,000

By Kent Davis (PJ-0752-09)

View Property

Vanguardia Model 02: Bay View Condo with Flexible Layout

Located at the entrance to…

Bedrooms
2
Bathrooms
2
Area
96.92 m2
For Sale

$485,000

By Zelda PJ-0752-09

View Property

Furnished Studio with Rental Program in La Central Flats

Located in La Central City…

Bedrooms
1
Bathrooms
1
Area
31 m2
For Sale

$195,444

By Nelly Pilch PJ 0752-09

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Featured Properties

42
1
Featured
Beach, Homes, Luxury Properties
For Sale
Image of the outside of this Vista Mar Oceanfront Golf Villa

Vista Mar Oceanfront Golf Villa For Sale

Vista Mar Marina, San Carlos, Panama
Added: June 15, 2026
Bedrooms
5
Bathrooms
6.5
Area
811 m2
For Sale

$1,950,000

Catherine (PJ-0752-09)
25
1
Featured
Beach, Condos and Apartments
For Sale
Image of balcony with ocean views in this condo for sale in Punta Caelo

Rare Oceanview 3 Bedroom Condo for Sale in Punta Caelo

Punta Caelo, San Carlos, Panama
Added: May 22, 2026
Bedrooms
3
Bathrooms
2.5
Area
143 m2
For Sale

$380,000

Catherine (PJ-0752-09)

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Owning a home is a keystone of wealthโ€ฆ both financial affluence and emotional security.

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August 15, 2026 Saturday!
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