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Property CitySanta Ana

1 to 6 out of 13 properties

Santa Ana Panama Real Estate – Historic Homes, Apartments & Investment Opportunities

Located next to Casco Viejo, Santa Ana is one of Panama City’s most historic neighborhoods, now undergoing an exciting period of revitalization. Known for its colonial architecture, traditional plazas, and authentic local culture, Santa Ana Panama real estate for sale and rent offers affordable apartments, renovated homes, and investment properties in the heart of the city.

With its central location, Santa Ana appeals to buyers and renters looking for city living at a more accessible price point, while still being just minutes from Panama’s top dining, nightlife, and cultural attractions in Casco Viejo.

Why Choose Santa Ana Panama?

Historic Character – Colonial buildings, traditional plazas, and vibrant street life.

Central Location – Walking distance to Casco Viejo and easy access to downtown.

Investment Potential – Increasing demand as revitalization projects continue.

Affordable Real Estate – More accessible pricing compared to Casco Viejo.

Types of Properties in Santa Ana

Restored Colonial Homes for Sale – Charming residences with historic details.

Apartments & Condos for Sale – Renovated units in boutique buildings.

Homes & Apartments for Rent – Long-term and short-term rental options.

Investment Properties – High rental demand among young professionals and expats.

Land for Development – Opportunities for new projects in a growing district.

Living in Santa Ana Panama

Life in Santa Ana blends old-world charm with modern convenience. Residents enjoy access to local markets, historic plazas, and a growing café and restaurant scene, all within walking distance of Casco Viejo. As revitalization projects continue, Santa Ana is quickly becoming one of the most dynamic and expat-friendly neighborhoods in Panama City, making it a smart choice for both lifestyle and investment.

Interested in Santa Ana Panama real estate?
Browse our listings of homes, apartments, and investment properties for sale and rent in Santa Ana and let Panama Equity’s experts guide you through this fast-growing neighborhood.

View Property

Furnished Studio with Rental Program in La Central Flats

Located in La Central City…

Bedrooms
1
Bathrooms
1
Area
31 m2
For Sale

$195,444

By Nelly Pilch PJ 0752-09

View Property

Income-Generating Condo in Santa Ana

Looking for an investment property…

Bedrooms
2
Bathrooms
2
Area
54 m2
For Sale

$302,127

By Nelly Pilch PJ 0752-09

View Property

La Central Studio A303 in Santa Ana for Sale

The La Central City Flats…

Bedrooms
1
Bathrooms
1
Area
31 m2
For Sale

$198,676

By Nelly Pilch PJ 0752-09

View Property

La Central A311: 2-Bedroom Condo with Lock-Off in Santa Ana

Looking for a property that…

Bedrooms
2
Bathrooms
2
Area
54 m2
For Sale

$316,451

By Nelly Pilch PJ 0752-09

View Property

La Union Corner Condo For Sale Gran Central

This 3-bedroom, 2-bathroom corner condo…

Bedrooms
3
Bathrooms
2
Area
107 m2
For Sale

$426,553

By Matthew Marx PN 6051

View Property

La Union Gran Central 2 Bedroom Lock-Off Condo

This 2-bedroom, 2-bathroom condo for…

Bedrooms
2
Bathrooms
2
Area
79 m2
For Sale

$319,908

By Ruben (PN-2946)

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Featured Properties

24
1
Featured
City, Homes, Luxury Properties
For Sale
Image of the outside of this house for sale in Los Senderos de Camino de Cruces

Quiet Family Home in Los Senderos de Camino de Cruces, Clayton

Calle Los Senderos, Residencial Senderos de Camino de Cruces, Ancón, Distrito de Panamá, Provincia de Panamá, 0000, Panamá
Added: October 15, 2025
Bedrooms
4
Bathrooms
5.5
Area
523.06 m2
For Sale

$1,300,000

Matthew Marx Matthew Marx PN 6051
21
1
Featured
Condos and Apartments, Beach
For Sale
Image of balcony with two chairs, a table and chairs and views of the green spaces and ocean in this condo in Galeones

Ensenada Beach Condo for Sale in San Carlos with Ocean Views

Ensenada, San Carlos, Panamá Oeste, Panama
Added: September 12, 2025
Bedrooms
2
Bathrooms
2
Area
97 m2
For Sale

$250,000

Catherine (PJ-0752-09)

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